Depression

Also known as: Major Depressive Disorder, Clinical Depression

Category: Mental HealthICD-10: F32

Need to talk? Tele-MANAS 14416 (free, 24x7)

Depression is a common, treatable mental health condition causing persistent low mood and loss of interest that affects daily life.

Symptoms

  • Persistent sadness
  • Loss of interest
  • Sleep changes
  • Appetite changes
  • Tiredness
  • Feelings of worthlessness

Causes

  • Mix of genetic, biological and life factors

Risk factors

  • Stress
  • Family history
  • Chronic illness
  • Loss or trauma

Complications

  • Self-harm
  • Substance use

Treatment overview

Talk therapy, antidepressant medicines, or both; recovery is common with treatment.

Prevention

  • Social connection
  • Exercise
  • Early help

When to see a doctor

If low mood lasts more than 2 weeks. If you are having thoughts of self-harm, call Tele-MANAS 14416 now.

Specialists who treat it

Frequently asked questions

What are the symptoms of Depression?

Persistent sadness, Loss of interest, Sleep changes, Appetite changes, Tiredness, Feelings of worthlessness

What causes Depression?

Mix of genetic, biological and life factors

How is Depression treated?

Talk therapy, antidepressant medicines, or both; recovery is common with treatment.

How can Depression be prevented?

Social connection, Exercise, Early help

Medically reviewed by

Medical review pending

Last updated

9 October 2026

Sources

  • World Health Organization fact sheets
  • ICMR and MoHFW national guidelines
  • National Centre for Disease Control (NCDC)

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.