Glimepiride

System: AllopathyClass: Sulfonylurea AntidiabeticComposition: GlimepiridePrescription: Prescription OnlyEssential medicine (NLEM): Yes

Glimepiride lowers blood sugar by making the pancreas release more insulin.

Common brands

  • Amaryl
  • Glimy
  • Gemer (with metformin)

Dosage forms

  • Tablet

Uses

  • Type 2 diabetes

How it works

Stimulates insulin release from the pancreas.

How to take

Take with breakfast; do not skip meals after taking it.

Common side effects

  • Low blood sugar
  • Weight gain

Serious side effects — get medical help

  • Severe hypoglycaemia
  • Allergic skin reactions

Who should not take it

  • Type 1 diabetes
  • Severe kidney or liver disease
  • Sulfa allergy

Interactions

  • Alcohol
  • Beta-blockers can mask low sugar
  • Fluconazole

Pregnancy & breastfeeding

Not used in pregnancy; insulin preferred.

Alcohol & driving

Avoid alcohol; check sugar before driving.

Storage

Store below 30°C.

Used for these conditions

Brands available in India

Frequently asked questions

What is Glimepiride used for?

Type 2 diabetes

What are the side effects of Glimepiride?

Low blood sugar, Weight gain

How should I take Glimepiride?

Take with breakfast; do not skip meals after taking it.

Who should not take Glimepiride?

Type 1 diabetes, Severe kidney or liver disease, Sulfa allergy

Medically reviewed by

Medical review pending

Last updated

9 October 2026

Sources

  • National List of Essential Medicines (NLEM) 2022, MoHFW
  • National Formulary of India, Indian Pharmacopoeia Commission
  • CDSCO approved drug information

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.