Omeprazole

System: AllopathyClass: Proton Pump Inhibitor (PPI)Composition: OmeprazolePrescription: Prescription OnlyEssential medicine (NLEM): Yes

Omeprazole was one of the first PPIs and is still widely used for acidity, GERD and ulcers.

Common brands

  • Omez

Dosage forms

  • Capsule
  • Injection

Uses

  • Acidity and GERD
  • Peptic ulcer
  • H. pylori (with antibiotics)

How it works

Blocks the stomach acid pump.

How to take

Take 30-60 minutes before breakfast.

Common side effects

  • Headache
  • Diarrhoea
  • Nausea

Serious side effects — get medical help

  • Low magnesium and B12 with long use
  • C. difficile diarrhoea

Who should not take it

  • Allergy to PPIs

Interactions

  • Clopidogrel (reduces its effect)
  • Methotrexate

Pregnancy & breastfeeding

Use if prescribed.

Alcohol & driving

No specific restriction.

Storage

Store below 30°C.

Used for these conditions

Prescribed by

Brands available in India

Frequently asked questions

What is Omeprazole used for?

Acidity and GERD, Peptic ulcer, H. pylori (with antibiotics)

What are the side effects of Omeprazole?

Headache, Diarrhoea, Nausea

How should I take Omeprazole?

Take 30-60 minutes before breakfast.

Who should not take Omeprazole?

Allergy to PPIs

Medically reviewed by

Medical review pending

Last updated

11 October 2026

Sources

  • National List of Essential Medicines (NLEM) 2022, MoHFW
  • National Formulary of India, Indian Pharmacopoeia Commission
  • CDSCO approved drug information

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.