Domperidone
Domperidone relieves nausea, vomiting and bloating by helping the stomach empty faster. It is often combined with a PPI in India.
Common brands
- Domstal
- Pan-D (with pantoprazole)
Dosage forms
- Tablet
- Suspension
Uses
- Nausea and vomiting
- Bloating and fullness
- Acidity (with PPI)
How it works
Blocks dopamine receptors in the gut and the brain vomiting centre.
How to take
Take 15-30 minutes before meals, at the lowest dose for the shortest time.
Common side effects
- Dry mouth
- Headache
- Abdominal cramps
Serious side effects — get medical help
- Heart rhythm problems, especially in older people or at high doses
Who should not take it
- Heart rhythm disorders
- Moderate to severe liver disease
- Prolactin-secreting tumour
Interactions
- Ketoconazole, erythromycin and other QT-prolonging drugs
Pregnancy & breastfeeding
Avoid unless prescribed.
Alcohol & driving
No specific restriction.
Storage
Store below 30°C.
Used for these conditions
Prescribed by
Brands available in India
Frequently asked questions
What is Domperidone used for?
Nausea and vomiting, Bloating and fullness, Acidity (with PPI)
What are the side effects of Domperidone?
Dry mouth, Headache, Abdominal cramps
How should I take Domperidone?
Take 15-30 minutes before meals, at the lowest dose for the shortest time.
Who should not take Domperidone?
Heart rhythm disorders, Moderate to severe liver disease, Prolactin-secreting tumour
Medically reviewed by
Medical review pending
Last updated
11 October 2026
Sources
- National List of Essential Medicines (NLEM) 2022, MoHFW
- National Formulary of India, Indian Pharmacopoeia Commission
- CDSCO approved drug information
This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.