Sitagliptin
System: AllopathyClass: DPP 4 Inhibitor AntidiabeticComposition: SitagliptinPrescription: Prescription OnlyEssential medicine (NLEM): No
Sitagliptin helps control blood sugar in type 2 diabetes with a low risk of hypoglycaemia; generics became widely available in India after patent expiry.
Common brands
- Januvia
- Istavel
- Janumet (with metformin)
Dosage forms
- Tablet
Uses
- Type 2 diabetes
How it works
Increases incretin hormones that boost insulin after meals.
How to take
Once daily, with or without food.
Common side effects
- Headache
- Cold-like symptoms
Serious side effects — get medical help
- Pancreatitis (rare)
- Joint pain
- Severe allergic reactions
Who should not take it
- Type 1 diabetes
- History of pancreatitis (discuss with doctor)
Interactions
- Sulfonylureas and insulin (low sugar risk)
Pregnancy & breastfeeding
Not recommended in pregnancy.
Alcohol & driving
No specific restriction.
Storage
Store below 30°C.
Used for these conditions
Prescribed by
Brands available in India
Frequently asked questions
What is Sitagliptin used for?
Type 2 diabetes
What are the side effects of Sitagliptin?
Headache, Cold-like symptoms
How should I take Sitagliptin?
Once daily, with or without food.
Who should not take Sitagliptin?
Type 1 diabetes, History of pancreatitis (discuss with doctor)
Medically reviewed by
Medical review pending
Last updated
11 October 2026
Sources
- National List of Essential Medicines (NLEM) 2022, MoHFW
- National Formulary of India, Indian Pharmacopoeia Commission
- CDSCO approved drug information
This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.