Janumet 50/500

Janumet 50/500 is a tablet made by MSD that contains Sitagliptin + Metformin (50 mg + 500 mg). It is commonly used for: Type 2 diabetes; Prediabetes (selected); PCOS.

Composition

Sitagliptin + Metformin

Strength

50 mg + 500 mg

Form

Tablet

Manufacturer

MSD

System

Allopathy

Type

Combination

Prescription

Prescription onlyPrescription required

Check the current MRP printed on the pack or with your pharmacist; prices change and many are capped by NPPA.

Uses

  • Type 2 diabetes
  • Prediabetes (selected)
  • PCOS

About Sitagliptin

Sitagliptin: How to take

Once daily, with or without food.

Sitagliptin: Common side effects

  • Headache
  • Cold-like symptoms

Sitagliptin: Serious side effects — get medical help

  • Pancreatitis (rare)
  • Joint pain
  • Severe allergic reactions

Sitagliptin: Who should not take it

  • Type 1 diabetes
  • History of pancreatitis (discuss with doctor)

Sitagliptin: Interactions

  • Sulfonylureas and insulin (low sugar risk)

Sitagliptin: Pregnancy & breastfeeding

Not recommended in pregnancy.

Sitagliptin: Alcohol & driving

No specific restriction.

Sitagliptin: Storage

Store below 30°C.

About Metformin

Metformin: How to take

Take with or after meals; start low and increase as advised to reduce stomach upset.

Metformin: Common side effects

  • Nausea
  • Diarrhoea
  • Metallic taste
  • Low B12 with long use

Metformin: Serious side effects — get medical help

  • Lactic acidosis (rare; higher risk with kidney failure)

Metformin: Who should not take it

  • Severe kidney disease
  • Before contrast scans or surgery (temporary stop as advised)
  • Heavy alcohol use

Metformin: Interactions

  • Iodinated contrast
  • Alcohol

Metformin: Pregnancy & breastfeeding

Used in pregnancy only under specialist care.

Metformin: Alcohol & driving

Avoid heavy alcohol.

Metformin: Storage

Store below 30°C.

Other brands of Sitagliptin

Other brands of Metformin

Frequently asked questions

What is Janumet 50/500 used for?

Type 2 diabetes, Prediabetes (selected), PCOS

What is the composition of Janumet 50/500?

Sitagliptin + Metformin 50 mg + 500 mg

What are the side effects of Janumet 50/500?

Headache, Cold-like symptoms, Nausea, Diarrhoea, Metallic taste, Low B12 with long use

Who makes Janumet 50/500?

MSD

Medically reviewed by

Medical review pending

Last updated

11 October 2026

Sources

  • Manufacturer product information and pack label
  • CDSCO approved drug information
  • National Formulary of India

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.

This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.