Metformin
Metformin is the first-line medicine for type 2 diabetes and is also used in PCOS.
Common brands
- Glycomet
- Glucophage
- Obimet
Dosage forms
- Tablet
- Extended-release tablet
Uses
- Type 2 diabetes
- Prediabetes (selected)
- PCOS
How it works
Reduces liver glucose production and improves insulin sensitivity.
How to take
Take with or after meals; start low and increase as advised to reduce stomach upset.
Common side effects
- Nausea
- Diarrhoea
- Metallic taste
- Low B12 with long use
Serious side effects — get medical help
- Lactic acidosis (rare; higher risk with kidney failure)
Who should not take it
- Severe kidney disease
- Before contrast scans or surgery (temporary stop as advised)
- Heavy alcohol use
Interactions
- Iodinated contrast
- Alcohol
Pregnancy & breastfeeding
Used in pregnancy only under specialist care.
Alcohol & driving
Avoid heavy alcohol.
Storage
Store below 30°C.
Used for these conditions
Prescribed by
Brands available in India
Frequently asked questions
What is Metformin used for?
Type 2 diabetes, Prediabetes (selected), PCOS
What are the side effects of Metformin?
Nausea, Diarrhoea, Metallic taste, Low B12 with long use
How should I take Metformin?
Take with or after meals; start low and increase as advised to reduce stomach upset.
Who should not take Metformin?
Severe kidney disease, Before contrast scans or surgery (temporary stop as advised), Heavy alcohol use
Medically reviewed by
Medical review pending
Last updated
9 October 2026
Sources
- National List of Essential Medicines (NLEM) 2022, MoHFW
- National Formulary of India, Indian Pharmacopoeia Commission
- CDSCO approved drug information
This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.