Chlorpheniramine
Also known as: Chlorphenamine, CPM
System: AllopathyClass: Antihistamine (First Generation)Composition: Chlorpheniramine MaleatePrescription: OTCEssential medicine (NLEM): Yes
Chlorpheniramine is an older antihistamine found in many Indian cold and flu combinations.
Common brands
- Sinarest (combination)
- D-Cold Total (combination)
- Cheston Cold (combination)
Dosage forms
- Tablet
- Syrup
Uses
- Runny nose and sneezing
- Allergies
- Cold symptoms (in combinations)
How it works
Blocks histamine H1 receptors.
How to take
As directed on the pack or by your doctor.
Common side effects
- Drowsiness
- Dry mouth
- Blurred vision
Serious side effects — get medical help
- Confusion in older people
- Paradoxical excitation in children
Who should not take it
- Children under 2
- Glaucoma
- Urinary retention
Interactions
- Alcohol and sedatives
- MAO inhibitors
Pregnancy & breastfeeding
Ask a doctor in pregnancy.
Alcohol & driving
Causes drowsiness - do not drive; avoid alcohol.
Storage
Store below 30°C.
Used for these conditions
Prescribed by
Brands available in India
Frequently asked questions
What is Chlorpheniramine used for?
Runny nose and sneezing, Allergies, Cold symptoms (in combinations)
What are the side effects of Chlorpheniramine?
Drowsiness, Dry mouth, Blurred vision
How should I take Chlorpheniramine?
As directed on the pack or by your doctor.
Who should not take Chlorpheniramine?
Children under 2, Glaucoma, Urinary retention
Medically reviewed by
Medical review pending
Last updated
11 October 2026
Sources
- National List of Essential Medicines (NLEM) 2022, MoHFW
- National Formulary of India, Indian Pharmacopoeia Commission
- CDSCO approved drug information
This information is for general awareness and does not replace advice from a qualified doctor. Do not start, stop or change any medicine without medical advice.